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Selective synthesis of 1,3‐Di(pyridylimino)‐isoindolines from tetracyanobenzene
Author(s) -
Mandal Sanat K.,
Thompson Laurence K.,
Ray Soma
Publication year - 1992
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570290653
Subject(s) - isoindoline , chemistry , combinatorial chemistry , medicinal chemistry
The synthesis of substituted 1,3‐bis‐(2‐pyridylimino)isoindoline 4 from 1,2,4,5‐tetracyanobenzene and 2,6‐diaminopyridine under mild and dilute conditions constitutes a new approach to produce a functionalized compound 4. The synthesis of an analogous compound 5 from 1,2,4,5‐tetracyanobenzene and 2‐amino‐6‐methylpyridine is also described.