Synthesis of indolizines and pyrrolo[2,1‐ b ]azoles from 2‐pyridylmagnesium bromide and 2‐lithiated azoles using tris(alkylthio)‐cyclopropenyl cations as a three‐carbon building block | Zendy

Kojima Hideo | Zendy; Yamamoto Kazuhiko | Zendy; Kinoshita Yasuo | Zendy; Inoue Hiroo | Zendy

Premium

Synthesis of indolizines and pyrrolo[2,1‐ b ]azoles from 2‐pyridylmagnesium bromide and 2‐lithiated azoles using tris(alkylthio)‐cyclopropenyl cations as a three‐carbon building block

Author(s) -

Kojima Hideo,

Yamamoto Kazuhiko,

Kinoshita Yasuo,

Inoue Hiroo

Publication year - 1992

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570290618

Subject(s) - chemistry , tris , bromide , block (permutation group theory) , medicinal chemistry , combinatorial chemistry , organic chemistry , biochemistry , geometry , mathematics

A convenient method for the preparation of indolizines 3 and 4 and pyrrolo[2,1‐ b ]azoles 7a‐e from 2‐pyridylmagnesium bromide and 2‐lithiated azoles 6a‐e , respectively, was developed by using tris( tert ‐butylthio)‐ and tris(isopropylthio)cyclopropenyl cations 1 and 2 as a three‐carbon building block.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research