Synthesis and antibacterial activity of new 5‐substituted 1‐cyclopropyl‐6‐fluoro‐7‐piperazinyl‐1,4‐dihydro‐4‐oxo‐1,8‐naphthyridine‐3‐carboxylic acids | Zendy

Remuzon Philippe | Zendy; Bouzard Daniel | Zendy; Di Cesare Pierre | Zendy; Dussy Christian | Zendy; Jacquet JeanPierre | Zendy; Jaegly Alexandre | Zendy

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Synthesis and antibacterial activity of new 5‐substituted 1‐cyclopropyl‐6‐fluoro‐7‐piperazinyl‐1,4‐dihydro‐4‐oxo‐1,8‐naphthyridine‐3‐carboxylic acids

Author(s) -

Remuzon Philippe,

Bouzard Daniel,

Di Cesare Pierre,

Dussy Christian,

Jacquet JeanPierre,

Jaegly Alexandre

Publication year - 1992

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570290453

Subject(s) - chemistry , antibacterial activity , carboxylic acid , stereochemistry , medicinal chemistry , combinatorial chemistry , organic chemistry , bacteria , genetics , biology

The 5‐hydroxymethyl and the 5‐formyl‐1‐cyclopropyl‐6‐fluoro‐7‐piperazinyl‐1,4‐dihydro‐4‐oxo‐1,8‐naphthyridine‐3‐carboxylic acids have been prepared via a 5‐trimethylsilyl group and were tested in vitro as potential antibacterials.

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