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Synthesis of indoles via amidoselenation
Author(s) -
Izumi Taeko,
Sugano Miwa,
Konno Touru
Publication year - 1992
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570290437
Subject(s) - chemistry , combinatorial chemistry , stereochemistry , organic chemistry
The reaction of 2‐styrylacetanilides (2) with N ‐phenylselenosuccinimide affords 1‐ N ‐acetyl‐2‐phenyl‐3‐phenylselenoindoles (3) and 1‐ N ‐acetyl‐2‐phenylindoles (4) . The reaction of 2‐vinylacetanilides (5) with phenylselenenyl bromide proceeds to form indoles via an intramolecular amidoselenation.
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