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Synthesis of 7‐ and 5,7‐substituted‐6‐fluoro‐2‐methyl‐1,2,3,4‐tetrahydroquinolines: Convenient precursors of quinolone antibacterial agents
Author(s) -
Bouyssou Pascal,
Le Goff Corinne,
Chenault Jacques
Publication year - 1992
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570290436
Subject(s) - chemistry , quinolone , combinatorial chemistry , antibacterial activity , stereochemistry , antibiotics , bacteria , biochemistry , biology , genetics
An original procedure to obtain substitution at the 7 or 5, 7 positions on 6‐halogenated tetrahydroquinaldines is described. The title products are a new class of precursors of quinolone antibacterial agents.