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Halovinylsulfones 4 . Synthesis and some reactions of 2‐phenylsulfonyl‐2‐propenyl isothiocyanate
Author(s) -
Yamamoto Iwao,
Kajiwara Kouji,
Fujimoto Tetsuya,
Ohta Kazutika
Publication year - 1992
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570290238
Subject(s) - chemistry , isothiocyanate , propenyl , thiocyanate , yield (engineering) , sulfone , allyl isothiocyanate , medicinal chemistry , organic chemistry , materials science , metallurgy
The title compound, isothiocyanate 2 , was obtained in good yield from the reaction of α‐chloromethylvinyl‐sulfone 1 with lead thiocyanate. The isothiocyanate 2 was reacted with aromatic amines to give 2‐amino‐5,6‐dihydro‐4 H ‐1,3‐thiazines 3 in good to moderate yields. The formation pathways are discussed.