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Reaction of tris(alkylthio)cyclopropenyl cations with 2‐pyridylmagnesium bromide as a new route to indolizines
Author(s) -
Kojima Hideo,
Kinoshita Yasuo,
Matsumura Noboru,
Inoue Hiroo
Publication year - 1991
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570280848
Subject(s) - tris , chemistry , bromide , tetrahydrofuran , medicinal chemistry , organic chemistry , solvent , biochemistry
The reaction of tris(isopropylthio)‐ and tris( tert ‐butylthio)cyclopropenylium perchlorates 1a and 1b with 2‐pyridylmagnesium bromide in dry tetrahydrofuran at room temperature gave 1,2,3‐tris(isopropylthio)‐ and 1,2,3‐tris( tert ‐butylthio)indolizines 2a and 2b , respectively, in high yields.