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An unusual reaction at C‐3 of 4‐methoxy‐6‐methyl‐2‐pyrone
Author(s) -
MorenoMañas M.,
Pleixats R.
Publication year - 1991
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570280842
Subject(s) - chemistry , pyrone , lactone , condensation , ether , medicinal chemistry , organic chemistry , condensation reaction , reaction conditions , catalysis , physics , thermodynamics
Triacetic acid lactone methyl ether, 4, can be lithiated at C‐3 under kinetically controlled conditions. Further reaction with ( E )‐2‐methyl‐3‐(4‐nitrophenyl)propenal results in an unusual condensation at C‐3.
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