Premium
Heterocycles. XXVI . A total synthesis of optically pure (+)‐catechin pentaacetate
Author(s) -
Urano Mieko,
Kagawa Hitoshi,
Harigaya Yoshihiro,
Li Shaoshun,
Onda Masayuki
Publication year - 1991
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570280807
Subject(s) - chemistry , reagent , optically active , epoxide , total synthesis , catechin , stereochemistry , medicinal chemistry , organic chemistry , catalysis , polyphenol , antioxidant
A total synthesis of optically pure (+)‐catechin pentaacetate has been established using the (‐)‐chalcon epoxide (100% ee) derived from 3,4,2′,4′,6′‐pentakis(methoxymethoxy)chalcon as the starting material. The optical purity of the product is confirmed by 1 H nmr analysis in the presence of a shift reagent.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom