Premium
Bond‐switch rearrangement of 3‐oxo‐Δ 4 ‐1,2,4‐thiadiazolin‐5‐yl ureas
Author(s) -
L'Abbé Gerrit,
Albrecht Ernestine,
Toppet Suzanne
Publication year - 1991
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570280627
Subject(s) - chemistry , isocyanate , yield (engineering) , medicinal chemistry , stereochemistry , computational chemistry , organic chemistry , materials science , metallurgy , polyurethane
5‐Amino‐3‐oxo‐Δ 4 ‐1,2,4‐thiadiazolines 5a,b react with isocyanates to yield 1,2,4‐thiadiazolidine derivatives 9a‐d via bond switching of the corresponding isomers 7 . The same type of products 9e‐m was obtained by treatment of 5‐amino‐1,2,3,4‐thiatriazoles 6a‐d with two equivalents of isocyanate.