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A macrocyclic amide from dehydrochlorination of indole‐3‐carbonyl chloride
Author(s) -
Oliver J. E.,
Waters R. M.,
Lusby W. R.,
FlippenAnderson J. L.
Publication year - 1991
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570280619
Subject(s) - chemistry , tetramer , ketene , amide , indole test , ring (chemistry) , mass spectrometry , infrared spectroscopy , nuclear magnetic resonance spectroscopy , infrared , single crystal , crystal structure , stereochemistry , polymer chemistry , medicinal chemistry , crystallography , organic chemistry , physics , chromatography , optics , enzyme
Indolyl‐3‐ketene 3 was generated from two precursors and was found to form a symmetrical tetramer 4 consisting of a sixteen‐membered ring amide. The tetramer was characterized by mass spectrometry, infrared, 1 H and 13 C‐nmr spectroscopy, and single crystal X‐ray crystallography.