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Synthesis of 2‐amino‐2‐deoxo‐5‐deazaflavins and related compounds
Author(s) -
Aoyagi Takeshi,
Yanada Reiko,
Bessho Kiyoshi,
Yoneda Fumio,
Armarego W. L. F.
Publication year - 1991
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570280611
Subject(s) - chemistry , stereochemistry , combinatorial chemistry
10‐Alkyl‐2‐amino‐2‐deoxo‐5‐deazaflavins were prepared by the condensation of 2‐amino‐6‐chloro‐5‐formylpyrimidin‐4(3 H )‐one with the corresponding N ‐alkylanilines. 2‐Amino‐10‐ p ‐tolyl‐2‐deoxo‐5‐deazaflavin was prepared by the condensation of 2‐amino‐6‐ p ‐toluidinopyrimidin‐4(3 H )‐one with o ‐chlorobenzaldehyde. Some reactivities of 2‐aminopyrimidin‐4(3 H )‐ones are described.
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