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Synthesis of novel c ‐hetero‐fused thiophene derivatives
Author(s) -
Rangnekar D. W.,
Mavlankar S. V.
Publication year - 1991
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570280544
Subject(s) - chemistry , ethylenediamine , formamide , thiophene , ethylene glycol , condensation , sodium carbonate , dimethyl formamide , ethylene diamine , organic chemistry , combinatorial chemistry , sodium , nuclear chemistry , physics , solvent , thermodynamics
An efficient synthesis of novel 5‐(4‐nitrophenyl)‐2‐benzoxazol‐2‐yl‐ c ‐hetero‐fused thiophenes was achieved by the condensation of 5‐(4‐nitrophenyl)‐2‐benzoxazol‐2‐yl‐3,4‐dichlorothiophene with ethylene glycol, ethylenediamine, substituted thioamides and 2‐mercaptobenzimidazole using sodium carbonate in refluxing dimethyl formamide.