Premium
Synthesis of 3,5‐disubstituted 1,2,4‐triazoles containing trimethoxyphenyl groups: Potential antagonists of platelet activating factor
Author(s) -
Ares Jeffrey J.,
Messier Renee J.,
Kornecki Elizabeth
Publication year - 1991
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570280507
Subject(s) - chemistry , triazole , combinatorial chemistry , platelet activating factor , stereochemistry , factor (programming language) , organic chemistry , programming language , medicine , computer science
In an effort to develop a new class of Platelet Activating Factor antagonists, 3,5‐disubstituted 1,2,4‐triazoles containing trimethoxyphenyl groups have been synthesized. The synthesis of symmetrical triazoles 5 and 6 , as well as two methods of synthesizing unsymmetrical triazole 7 , are reported.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom