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Synthesis of condensed quinoxalines
Author(s) -
Sabnis R. W.,
Rangnekar D. W.
Publication year - 1991
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570280445
Subject(s) - quinoxaline , chemistry , conjugated system , pyridine , enol , diphenylamine , organic chemistry , medicinal chemistry , combinatorial chemistry , polymer , catalysis
A novel efficient synthesis of fluorescent, fused quinoxalines was achieved. 6‐Triazolylthiazolo[4,5‐ b ]quinoxalines were synthesized by the diazotisation of 6‐amino‐2‐methylthiazolo[4,5‐ b ]quinoxaline and coupling with selected aromatic amines followed by air oxidation. Diazotised aryl amines were coupled with 6‐amino‐2‐methylthiazolo[4,5‐ d ]quinoxaline followed by subsequent air oxidation afforded 1,2,3‐triazolo[5,4‐ f ]quinoxalino[2,3‐ d ]thiazoles. 6‐Amino‐2‐methylthiazolo[4,5‐ b ]quinoxaline was condensed with conjugated enol ethers followed by cyclization in dowtherm resulted in thiazolo[4,5‐ b ]quinoxalino[6,5‐ b ]pyridine.