Reaction of α,β‐unsaturated carbodiimides with enamines leading to fused pyridine derivatives | Zendy

Noguchi Michihiko | Zendy; Onimura Kenjiro | Zendy; Isomura Yuji | Zendy; Kajigaeshi Shoji | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Reaction of α,β‐unsaturated carbodiimides with enamines leading to fused pyridine derivatives

Author(s) -

Noguchi Michihiko,

Onimura Kenjiro,

Isomura Yuji,

Kajigaeshi Shoji

Publication year - 1991

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570280409

Subject(s) - chemistry , pyridine , isocyanate , ring (chemistry) , amine gas treating , enamine , medicinal chemistry , organic chemistry , catalysis , polyurethane

The treatment of (5,5‐dimethyl‐3‐oxo‐1‐cyclohexenyl)iminotriphenylphosphorane ( 2 ) with phenyl isocyanate ( 3a ) gave N ‐(5,5‐dimethyl‐3‐oxo‐1‐cyclohexenyl)‐ N' ‐phenylcarbodiimide ( 4a ) in situ . The reaction of 4a with enamines proceeded smoothly to afford the pyridine ring formation with the elimination of amine. This means that 4a is regarded as a new class of 2‐aza‐1,3‐butadiene. The scopes and limitation of this reaction are also discussed.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research