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Products from Furans. XVI . Novel synthetic routes to sympathomimetic amine analogues via 6‐hydroxy‐2 H ‐pyran‐3(6 H )‐ones
Author(s) -
Georgiadis Minas P.,
Haroutounian Serkos A.,
Couladouros Elias A.,
Apostolopoulos Costas D.,
Chondros Kostas P.
Publication year - 1991
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570280325
Subject(s) - chemistry , pyran , amine gas treating , ring (chemistry) , stereochemistry , organic chemistry , combinatorial chemistry
Novel heterocyclic analogues mimicking compounds with antipsychotic activity (sympathomimetic amines) were synthesized. These compounds contain the phenyl‐substituted pyran ring system as a consequence of their common route of preparation. Furthermore an example of the synthetic route for preparing compounds having the features of both β‐hydroxy‐β‐phenylethylamine and GABA is also presented.