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Nitration of dithieno[3,4‐ b :3′,2′‐ d ]pyridine and dithieno[2,3‐ b :3′,2′‐ d ]pyridine
Author(s) -
Gronowitz Salo,
Szabo Kalman J.,
Oluwadiya James O.
Publication year - 1991
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570280227
Subject(s) - nitration , pyridine , chemistry , thiophene , ring (chemistry) , nitro , nitro compound , nuclear magnetic resonance spectroscopy , medicinal chemistry , stereochemistry , organic chemistry , alkyl
The nitration of dithieno[3,4‐ b :3′,2′‐ d ]pyridine ( 2 ) and dithieno[2,3‐ b :3′,2′‐ d ]pyridine ( 3 ) has been studied. Nitration of 2 occurred in both positions of the c‐fused thiophene ring, while 3 was predominantly substituted in the 2‐position. The structures of the nitro derivatives were proven by extensive use of 1 H and 13 C nmr spectroscopy.