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Caractérisation de nouveaux dérivés et analogues de la nétropsine et identification de leurs intermédiaires de synthèse par spectrométrie de masse FAB
Author(s) -
Aubagnac JeanLouis,
Debart Françoise,
Mrani Driss,
Gosselin Gilles,
Rayner Bernard,
Imbach JeanLouis
Publication year - 1991
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570280126
Subject(s) - chemistry , stereochemistry , mass spectrum , ion , organic chemistry
The fast‐atom bombardment (FAB) mass spectra of a series of netropsin derivatives and analogues were examined in positive‐ion and when necessary negative‐ion modes. Behaviour of these derivatives was related to that of oligopeptides. Some compounds protected by t ‐butoxycarbonyl groups were also investigated using this technique and showed characteristic fragmentations.