Premium
Some fatty acids having an O ‐heterocycle in their terminal positions. II . ω‐(3‐Coumarinyl)alkanoic acids and ω‐(2‐chromonyl)alkanoic acids
Author(s) -
Yamaguchi Seiji,
Saitoh Miyuki,
Kawase Yoshiyuki
Publication year - 1991
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570280122
Subject(s) - chemistry , hydrolysis , ethyl ester , organic chemistry , medicinal chemistry , stereochemistry
Some ω‐3‐coumarinyl)alkanoic acids 1a , n = 3‐6 were synthesized by cyclization of corresponding ethyl o ‐formylphenyl alkanedioate 3 with DBU followed by hydrolysis. By a similar cyclization, some ω‐(2‐chromonyl)alkanoic acids 2a , n = 3‐6 were also obtained from the cyclization of corresponding o ‐acetylphenyl ethyl alkanedioate 4 .