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A study on m ‐chloroperbenzoic acid and lead tetraacetate oxidation of some 1‐aroyl‐4,5‐dihydro‐4,4‐dimethyl‐5‐methylene‐1 H ‐pyrazoles
Author(s) -
Mitkidou Sophia,
StephanidouStephanatou Julia
Publication year - 1991
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570280109
Subject(s) - chemistry , pyrazolones , methylene , medicinal chemistry , organic chemistry
1‐Aroyl‐4,5‐dihydro‐5‐methylene‐1 H ‐pyrazoles 1 are converted upon oxidation with m ‐chloroperbenzoic acid to the pyrazolones 2 . The same aroyl enamides 1 are also oxidized with LTA to form the acetoxy derivatives 7 and 8 . The reaction mechanisms are discussed.