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Acid‐catalyzed reactions of 1‐ and 3‐(α‐hydroxybenzyl)indolizines
Author(s) -
Miki Yasuyoshi,
Hiroishi Yuji,
Hachiken Hiroko,
Takemura Shoji
Publication year - 1991
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570280108
Subject(s) - chemistry , trifluoroacetic acid , dichloromethane , substituent , catalysis , organic chemistry , acid catalysis , medicinal chemistry , solvent
Treatment of 1‐(α‐hydroxybenzyl)‐ and 3‐(α‐hydroxybenzyl)indolizines with trifluoroacetic acid in dichloromethane gave phenylbis(α‐indolizinyl)methanes, bis[α‐(indolizinyl)benzyl] ethers and indolizines, depending upon the presence or absence of the substituent at the 2‐ or 5‐position and the reaction conditions used.