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A facile synthesis of 5,14‐methano‐16‐oxo‐1,5,6‐benzoxadiazonino[3,4‐ b ]quinoxalines by a 1,3‐dipolar cycloaddition reaction and an intramolecular alcoholysis
Author(s) -
Kurasawa Yoshihisa,
Kim Ho Sik,
Katoh Ritsuko,
Kawano Tae,
Takada Atsushi,
Okamoto Yoshihisa
Publication year - 1990
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570270763
Subject(s) - chemistry , quinoxaline , intramolecular force , cycloaddition , medicinal chemistry , 1,3 dipolar cycloaddition , organic chemistry , catalysis
The reaction of the hydrazones 5a‐c with 2‐chloroacrylonitrile gave the 1,2‐diazepino[3,4‐ b ]quinoxaline hydrochlorides 6a‐c , which were converted into the 5,14‐methano‐16‐oxo‐1,5,6‐benzoxadiazonino[3,4‐ b ]‐quinoxalines 7a‐c , respectively.
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