1,3‐dipolar cycloadditions of 2‐diazobutane, diazophenylmethane and 1‐diazo‐1‐phenylethane to azolopyridazines. The isolation of some primary and rearranged cycloadducts and their transformations into substituted pyrazolo[4,3‐ d ]azolopyridazines | Zendy

Huč Branko | Zendy; Furlan Borut | Zendy; Stanovnik Branko | Zendy; Tišsler Miha | Zendy

Premium

1,3‐dipolar cycloadditions of 2‐diazobutane, diazophenylmethane and 1‐diazo‐1‐phenylethane to azolopyridazines. The isolation of some primary and rearranged cycloadducts and their transformations into substituted pyrazolo[4,3‐ d ]azolopyridazines

Author(s) -

Huč Branko,

Furlan Borut,

Stanovnik Branko,

Tišsler Miha

Publication year - 1990

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570270754

Subject(s) - chemistry , diazo , cycloaddition , primary (astronomy) , medicinal chemistry , stereochemistry , 1,3 dipolar cycloaddition , organic chemistry , catalysis , physics , astronomy

The 1,3‐dipolar cycloaddition of 2‐diazobutane ( 2 ) to azolopyridazines 1 gave 9‐ethyl‐9‐methyl‐7,8‐dihydropyrazolo[4,3‐ d ]‐ 4 and 9‐ethyl‐9‐methyl‐9 H ‐pyrazolo[4,3‐ d ]azolopyridazines 5 . With diazophenylmethane ( 6 ) 7‐benzyl‐8‐phenyl‐7 H ‐ 12 and 8‐benzyl‐9‐phenyl‐8 H ‐pyrazolo[4,3‐ d ]azolopyridazines 13 were obtained, while with 1‐diazo‐1‐phenylethane ( 14 ) the primary cycloadducts 15 , and rearranged cycloadducts 16 and 17 were isolated in some instances and further transformed into 9‐methyl‐9‐phenyl‐9 H ‐pyrazolo[4,3‐ d ]azolopyridazines 18 .

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research