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Selective lateral metalation and electrophilic quenching of c‐4 functionalized isoxazoles. IX . Direct formation of the C‐N bond utilizing an electrophilic nitrogen source
Author(s) -
Mirzaei Yousef R.,
Balasubramaniam T. N.,
Lefler Barbara J.,
Natale N. R.
Publication year - 1990
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570270729
Subject(s) - chemistry , electrophile , metalation , quenching (fluorescence) , nitrogen , boron , medicinal chemistry , combinatorial chemistry , stereochemistry , organic chemistry , catalysis , fluorescence , physics , quantum mechanics
C‐5 Lithio‐alkylisoxazoles were quenched with dialkyl azodicarboxylates to form the C‐5 alkylhydrazine derivatives in synthetically useful yields.
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