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Heterocyclic X‐azolopyridine intermediates
Author(s) -
Viscardi Guido,
Savarino Piero,
Barni Ermanno,
Carpignano Rosarina
Publication year - 1990
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570270657
Subject(s) - chemistry , oxazole , acetic anhydride , acetylation , selectivity , acetic acid , chloride , acetyl chloride , organic chemistry , aminopyridines , medicinal chemistry , catalysis , biochemistry , gene
A series of heterocyclic coupling agents having tuned hydrophobic chains, has been prepared by reaction of diamino or hydroxy‐aminopyridines and p ‐aminosalicylic acid. The acetylation of amino group and hydroxyl in oxazole derivatives showed a selectivity depending on wheter acetic anhydride or acetyl chloride was used. Correlations between structure and spectroscopic data, including related compounds previously described, are reported.