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Pyridazines. LII . Novel 1,2‐diazine analogues of 2‐aminobenzophenone via directed lithiation
Author(s) -
Haider Norbert,
Heinisch Gottfried,
Kemetmüller Gudrun
Publication year - 1990
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570270622
Subject(s) - chemistry , diazine , pyridazine , aniline , medicinal chemistry , stereochemistry , combinatorial chemistry , organic chemistry
The preparation of novel pyridazine analogues of 2‐aminobenzophenone, namely 2‐(substituted)aminophenyl 3‐pyridazinyl ketones 2, 3, 4a,b , achieved by reaction of methyl 3‐pyridazinecarboxylate with ortho ‐lithiated aniline derivatives, is reported.