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Preparation and reactivity of polyfunctional phenazine derivatives
Author(s) -
Lehn JeanMarie,
Schmidt Frédéric,
Vigneron JeanPierre
Publication year - 1990
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570270620
Subject(s) - chemistry , azide , phenazine , reagent , nucleophile , yield (engineering) , reactivity (psychology) , derivative (finance) , phenols , organic chemistry , combinatorial chemistry , sodium azide , medicine , materials science , alternative medicine , pathology , economics , financial economics , metallurgy , catalysis
Treatment of 2,3,6,7‐tetramethylphenazine with N ‐bromosuccinimide under light irradiation afforded in good yield the tetrakis(bromomethyl) derivative. Weakly basic nucleophilic reagents such as thiols, phenols, amines and the azide anion allow the preparation of a variety of functionalized derivatives. Some 2,7‐disubstituted phenazines have also been obtained.