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Synthesis of benzimidazo‐substituted 3‐quinolinecarboxylic acids as antibacterial agents
Author(s) -
Bran̂a Miguel F.,
Castellano José M.,
Yunta María J. R.
Publication year - 1990
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570270503
Subject(s) - chemistry , antibacterial activity , in vitro , organic chemistry , combinatorial chemistry , bacteria , biochemistry , genetics , biology
The 6‐ and 7‐(1‐ethylbenzimidazolyl)‐substituted 1‐ethyl‐1,4‐dihydro‐4‐oxoquinoline‐3‐carboxylic acids were synthesized. Antibacterial activity was tested in vitro . Only one of the new compounds prepared showed slight antibacterial activity against one of the strains tested. So, they are of no interest as antibacterial agents.