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A New method for the synthesis of 4‐oxo‐4,5‐dihydrofuro[3,2‐ c ]quinoline
Author(s) -
Gronowitz Salo,
Timari Géza
Publication year - 1990
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570270465
Subject(s) - quinoline , chemistry , ring (chemistry) , closure (psychology) , bicyclic molecule , medicinal chemistry , stereochemistry , organic chemistry , economics , market economy
A new method for the synthesis of 4‐oxo‐4,5‐dihydrofuro[3,2‐ c ]quinoline is the Pd(0)‐catalyzed coupling of o ‐bromonitrobenzene with 3‐formyl‐2‐tributylstannylfuran, followed by reductive ring closure to furo[3,2‐ c ]quinoline N ‐oxide and rearrangement.