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Polycondensed nitrogen heterocycles. Part 23. Pyrrolo[3,2‐ c ]cinnolines by a japp‐klingemann type reaction
Author(s) -
Cirrincione Girolamo,
Almerico Anna Maria,
Aiello Enrico,
Dattolo Gaetano
Publication year - 1990
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570270430
Subject(s) - chemistry , cinnoline , intramolecular force , pyrrole , medicinal chemistry , chlorine , nitrogen , organic chemistry
Pyrrolo[3,2‐ c ]cinnoline derivatives were obtained by an unusual Japp‐Klingemann reaction involving an intramolecular azadehalogenation on the pyrrole nucleus. Such an azadehalogenation represents the first example of Japp‐Klingemann reaction in which the extrusion of positive chlorine ion is verified.