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Synthesis of novel 1 H ‐imidazo[5,1‐ B ][3]benzazepine‐1,3(2 H )‐dione and pyrimido[6,1‐ B ][3]benzazepine‐1,3,4(2 H )‐trione
Author(s) -
Gallaschun Randall J.,
Schnur Rodney C.
Publication year - 1990
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570270426
Subject(s) - benzazepine , chemistry , benzazepines , ring (chemistry) , oxalyl chloride , tricyclic , stereochemistry , medicinal chemistry , organic chemistry
Two novel tricyclic ring systems derived from 3‐benzazepines were synthesized; the first, a 6,7,5‐ring, 1 H ‐imidazo[5,1‐ b ][3]benzazepine‐1,3(2 H )‐dione was obtained using an unusual Stiles reaction while the second, an analogous 6,7,6‐ring, pyrimido[6,1‐ b ][3]benzazepine‐1,3,4(2 H )‐trione was prepared with base and oxalyl chloride.