Premium
A Novel synthesis of 6‐hydroxyalkyl‐and 6‐hydroxy‐aralkyl‐6 H ‐dibenz[ c,e ][1,2]oxaphosphorin 6‐Oxides
Author(s) -
Yamada Yoichi,
Yasuda Heinosuke,
Saito Toranosuke
Publication year - 1990
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570270405
Subject(s) - chemistry , medicinal chemistry , stereochemistry
A new strategy for the synthesis of 6‐hydroxyalkyl‐ and 6‐hydroxyaralkyl‐6 H ‐dibenz[ c,e ][1,2]oxaphosphorin 6‐oxides 3 was achieved by the reaction of 2‐(2‐hydroxyphenyl)phenylphosphonic acid ( 1 ) with various carbonyl compounds 2 . The desired products 3 were obtained in acceptable yields.