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Polycyclic N ‐hetero compounds. XXXII Synthesis and antidepressive evaluation of B‐homo‐11,13,15‐triazasteroids and their precursors
Author(s) -
Hirota Takashi,
Sasaki Kenji,
Ieno Katsuhiro,
Sekiya Yuhki,
Nakayama Taiji
Publication year - 1990
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570270352
Subject(s) - chemistry , stereochemistry , pyrimidine
Synthesis of 4‐(2‐hydroxyethylamino)‐6,7‐dihydro‐5 H ‐benzo[6,7]cyclohepta[1,2‐ d ]pyrimidine derivatives V and their cyclized products, B‐homo‐11,13,15‐triazasteroidal compounds VI and VII , are described. These products were screened to evaluate the antidepressive activity.