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Synthesis of new derivatives of β‐carboline‐hydantoin
Author(s) -
Braña Miguel F.,
Garrido Mercedes,
Rodriguez María L. López,
Miguel Pilar,
Morcillo M. José,
Riaño A.
Publication year - 1990
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570270342
Subject(s) - chemistry , hydantoin , acetone , alkyl , stereochemistry , medicinal chemistry , organic chemistry
Reaction of tetrahydro‐β‐carboline‐3‐carboxylic acids 4a‐c with alkyl and phenyl isocyanates in acetone provide the corresponding 2,5‐disubstituted 1,3‐dioxo‐6 H ‐1,2,3,5,11,11a‐hexahydroimidazo[1,5‐ b ]‐β‐carbolines 2a‐r .