Intramolecular cyclization of 4‐acetyl‐2,2‐diethoxycarbonyl‐2,3‐dihydro‐1‐(2‐nitrobenzoyl)pyrrole by catalytic reduction | Zendy

De Caprariis P. | Zendy; De Martino G. | Zendy; Abignente E. | Zendy; Sacchi A. | Zendy

Premium

Intramolecular cyclization of 4‐acetyl‐2,2‐diethoxycarbonyl‐2,3‐dihydro‐1‐(2‐nitrobenzoyl)pyrrole by catalytic reduction

Author(s) -

De Caprariis P.,

De Martino G.,

Abignente E.,

Sacchi A.

Publication year - 1990

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570270341

Subject(s) - chemistry , pyrrole , intramolecular force , quinazoline , catalysis , catalytic hydrogenation , medicinal chemistry , dehydration , derivative (finance) , selective catalytic reduction , stereochemistry , organic chemistry , biochemistry , financial economics , economics

Catalytic hydrogenation of 4‐acetyl‐2,2‐dicthoxycarbonyl‐2,3‐dihydro‐1‐(2‐nitrobenzoyl)pyrrole 2 afforded 3‐acetyl‐1,1‐diethoxycarbonyl‐1,2,3,3a,4,9‐hexahydro‐9‐oxopyrrolo[2,1‐ b ]quinazoline 3 and the 4‐hydroxy derivative 4 , together with two tetrahydro analogs 5 and 6 of 3 . Compounds 5 and 6 were also obtained by dehydration of 4 .

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research