Premium
Picryl derivatives of 5‐nitro‐2,4‐dihydro‐3 H ‐1,2,4‐triazol‐3‐one
Author(s) -
Coburn Michael D.,
Lee KienYin
Publication year - 1990
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570270318
Subject(s) - chemistry , nitro , derivative (finance) , medicinal chemistry , stereochemistry , organic chemistry , alkyl , financial economics , economics
Treatment of 5‐nitro‐2,4‐dihydro‐3 H ‐1,2,4‐triazol‐3‐one ( 1 ) with picryl fluoride (PkF) in 1‐methyl‐2‐pyrrolidinone (NMP) gave a mixture of a monopicryl and a dipicryl derivative of 1 in a ratio of 2 :1 , respectively, regardless of the initial concentrations of 1 and PkF. The products were identified as 5‐nitro‐2‐picryl‐2,4‐dihydro‐3 H ‐1,2,4‐triazol‐3‐one ( 2 ) by X‐ray crystallography and 5‐nitro‐2,4‐dipicryl‐2,4‐dihydro‐3 H ‐1,2,4‐triazol‐3‐one ( 4 ) by 15 N labeling experiments.