Premium
Disentangling proton connectivity networks in highly overlapped 1 H‐NMR spectra of polynuclear aromatics using 1D‐HOHAHA
Author(s) -
Shockcor John P.,
Crouch Ronald C.,
Martin Gary E.,
Cherif Abdallah,
Luo JiannKuan,
Castle Raymond N.
Publication year - 1990
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570270263
Subject(s) - homonuclear molecule , chemistry , spectral line , two dimensional nuclear magnetic resonance spectroscopy , proton , nmr spectra database , quinoline , molecule , crystallography , nuclear magnetic resonance , stereochemistry , physics , organic chemistry , astronomy , quantum mechanics
One‐dimensional ( 1D ) variants of two‐dimensional ( 2D ) nmr techniques can frequently provide the required information in a much shorter period of time than the 2D experiment from which they were derived. Application of the 1D homonuclear Hartmann‐Hahn (1D‐HOHAHA) experiment to establish proton‐proton connectivity networks in highly overlapped four‐spin systems in the proton nmr spectra of polynuclear aromatics is described. Selective subspectra are contrasted to the data obtained in a COSY experiment on the same molecule, benzo[ f ][l]benzothieno [2,3 ‐ c ]quinoline. Results from the 1D‐HOHAHA technique are especially useful when component resonances from several spin systems are heavily overlapped. Relayed 1D‐HOHAHA provides the means of exploiting small, long range coupling pathways of polynuclear aromatics.