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Synthesis of 2‐ N ‐(benzo[ b ]thiophen‐2‐yl)benzo and heterofused‐1,2,3‐triazoles
Author(s) -
Sabnis R. W.,
Rangnekar D. W.
Publication year - 1990
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570270258
Subject(s) - chemistry , thiophene , medicinal chemistry , stereochemistry , organic chemistry
A novel efficient synthesis of 2‐ N ‐(benzo[ b ]thiophen‐2‐yl)benzo and heterofused‐1,2,3‐triazoles was achieved by the diazotisation of 2‐amino‐4,5,6,7‐tetrahydrobenzo[ b ]thiophene‐3‐carbonitrile and ethyl‐2‐amino‐4,5,6,7‐tetrahydrobenzo[ b ]thiophene‐3‐carboxylate and coupling with selected aromatic and heterocyclic amines followed by air oxidation in the presence of cupric acetate.