Bis heterocycles as potential chemotherapeutic agents.  X . Synthesis of bis(4‐arylthiosemicarbazido)‐, bis(2‐arylamino‐1,3,4‐thiadiazol‐5‐yl) and bis(4‐aryl‐1,2,4‐triazolin‐3‐thione‐5‐yl)pentanes and related compounds | Zendy

Ram Vishnu J. | Zendy; Mishra Lallan | Zendy; Pandey N. H. | Zendy; Kushwaha D. S. | Zendy; Pieters Luc A. C. | Zendy; Vlietinck Arnold J. | Zendy

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Bis heterocycles as potential chemotherapeutic agents. X . Synthesis of bis(4‐arylthiosemicarbazido)‐, bis(2‐arylamino‐1,3,4‐thiadiazol‐5‐yl) and bis(4‐aryl‐1,2,4‐triazolin‐3‐thione‐5‐yl)pentanes and related compounds

Author(s) -

Ram Vishnu J.,

Mishra Lallan,

Pandey N. H.,

Kushwaha D. S.,

Pieters Luc A. C.,

Vlietinck Arnold J.

Publication year - 1990

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570270245

Subject(s) - chemistry , alkylation , hydrogen peroxide , aryl , medicinal chemistry , combinatorial chemistry , organic chemistry , catalysis , alkyl

Synthesis of several bis(4‐arylthiosemicarbazido‐ 1 , bis(2‐arylamino‐1,3,4‐thiadiazol‐5‐yl)‐ 5 and bis(4‐aryl‐1,2,4‐triazolin‐3‐thione‐5‐yl)‐ 2 pentanes is described. Sulphides 3 and sulphones 4 are also prepared from 2 by alkylation and subsequent oxidation with hydrogen peroxide respectively.

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