Synthesis of vinca alkaloids and related compounds.  XLVI.   . Formation of a new ring system | Zendy

Dancsó András | Zendy; KajtárPeredy Mária | Zendy; Szántay Csaba | Zendy

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Synthesis of vinca alkaloids and related compounds. XLVI. . Formation of a new ring system

Author(s) -

Dancsó András,

KajtárPeredy Mária,

Szántay Csaba

Publication year - 1989

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570260662

Subject(s) - chemistry , vinca , indole test , ring (chemistry) , cyclopropane , pictet–spengler reaction , stereochemistry , medicinal chemistry , organic chemistry , pharmacology , medicine

In the Pictet‐Spengler reaction of indole‐3‐propanamine 1 and diethyl‐(2‐formyl‐cyclopropane‐1,1‐dicar‐boxylate) 2 the formation of ethyl (1a,2,4,5,6,11,11b,11c‐octahydro‐2‐oxo‐1 H ‐cycloprop[3′,4′]pyrrolo[1,2′:1,2]‐azepino[3,4‐ b ]indole‐1a‐carboxylates) 3 and 4 was observed. Compounds 3 and 4 represent a new ring system.

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