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Dimerization of pyrazolyl‐5‐hydroxypyrrolidinones to tetrazocines
Author(s) -
Brinkmeyer Raymond S.,
Terando Norman H.
Publication year - 1989
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570260636
Subject(s) - chemistry , yield (engineering) , ring (chemistry) , stereochemistry , crystallography , organic chemistry , metallurgy , materials science
The dimerization of the hydroxypyrrolidinones 5 and 9 yield the tetrazocines 8 and 11 . In addition, in the case of compound 9 , the ring‐fused hexaazacyclododecane 12 was isolated. X‐ray diffraction analysis of compound 11 verified the dimeric structure of these products.