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Synthesis and study of chiral NADH models in the thieno[2,3‐ b ]pyridine series
Author(s) -
Bench R.,
Duflos J.,
Dupas G.,
Bourguig J.,
Queguiner G.
Publication year - 1989
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570260616
Subject(s) - chemistry , pyridine , thiophene , ring (chemistry) , electrophile , electrophilic substitution , stereochemistry , medicinal chemistry , organic chemistry , catalysis
Thieno[2,3‐ b ]pyridine derivatives, functionalized on the thiophene ring have been synthesized in two different ways: electrophilic substitution of thieno[2,3‐ b ]pyridine derivatives or construction of a pyridine ring starting from disubstituted thiophene compounds. The products obtained were used in the synthesis of chiral NADH models.