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Heterocyclic ring‐analogs of dihydropyridine calcium antagonists
Author(s) -
Taylor Michael D.,
Anderson Kevin R.,
Badger Edward W.
Publication year - 1989
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570260525
Subject(s) - chemistry , dihydropyridine , ring (chemistry) , furan , pyrrole , derivative (finance) , stereochemistry , calcium , combinatorial chemistry , organic chemistry , financial economics , economics
An improved synthesis of the 1,4‐dihydropyrazine derivative, 3, is described that involves the versatile 1,4‐diketointermediate, 9 . This intermediate was converted to several heterocyclic ring‐analogs of 1,4‐dihydropyridine in addition to 3 including derivatives of pyrrole and furan.
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