Premium
The synthesis of 3 H ‐1,2,4‐thiadiazolo[3,4‐ b ]benzothiazoles
Author(s) -
Potts Kevin T.,
Kane John M.
Publication year - 1989
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570260514
Subject(s) - benzothiazole , chemistry , ring (chemistry) , medicinal chemistry , chloride , stereochemistry , organic chemistry
2‐Aminobenzothiazole reacted with 1,1,1‐trichloromethanesulfenyl chloride yielding 1,1,1‐trichloro‐ N ‐(2‐benzothiazolyl)methanesulfenamide. Subsequent cyclization using either aromatic or heteroaromatic amines readily yielded derivatives of the 3 H ‐1,2,4‐thiadiazolo[3,4‐ b ]benzothiazole ring system. Spectral data and brominations of these benzothiazoles are described.