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Alkyl substituted 3‐PPP derivatives. Synthesis and biological investigation
Author(s) -
Tecle Haile,
Bergmeier Stephen C.,
Wise Lawrence D.,
Hershenson Fred M.,
Coughenour Linda L.,
Heffner Thomas G.
Publication year - 1989
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570260441
Subject(s) - chemistry , alkyl , phenol , organic chemistry , stereochemistry , medicinal chemistry
Synthesis of alkyl substituted derivatives of 3‐(1‐propyl)3‐piperidinyl)phenol ( 3‐PPP ), 2–8 , was carried out in an attempt to improve on the pharmacodynamic properties of 3‐PPP. No significant improvement was attained.