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The reductive repair of 1, 3‐dhnethylthymine bromohydrin into 1, 3‐dimethylthymine by 1, 5‐dihydro‐5‐deazaflavin or 1, 4‐dihydroquinoline
Author(s) -
Akiyama Taishin,
Tanaka Kiyoshi,
Yoneda Fumio
Publication year - 1989
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570260370
Subject(s) - chemistry , trifluoroacetic acid , medicinal chemistry , reductive elimination , combinatorial chemistry , organic chemistry , stereochemistry , catalysis
The reductive conversion of 1, 3‐dimethylthymine bromohydrin into 1, 3‐dimethylthymine by 10‐ethyl‐3‐methyl‐1, 5‐dihydro‐5‐deazaflavin or 1‐benzyl‐3‐carbamoyl‐1, 4‐dihydroquinoline has been achieved in the presence of trifluoroacetic acid.