Premium
Synthesis of new tricyclic ring systems containing the pyrimido[5, 4‐ b ][1, 4]oxazine skeleton
Author(s) -
Mátyus Péter,
Szalay Luca,
Kasztreiner Endre,
Jerkovich Gyula,
Rabloczky György
Publication year - 1989
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570260341
Subject(s) - chemistry , tricyclic , ring (chemistry) , oxazines , stereochemistry , skeleton (computer programming) , organic chemistry , computer science , programming language
Synthesis of derivatives 4 and 6 of two novel tricyclic ring systems, 1, 2, 4‐triazolo[3, 4‐ c ]pyrimido[5, 4‐ b ]‐[1, 4]oxazine and imidazo[1, 2‐ c ]pyrimido[5, 4‐ b ][1, 4]oxazine, respectively is described. Although the parent pyrimido[5, 4‐ b ]oxazines possess positive inotropic activity, the tricyclic compounds are practically inactive.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom