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Synthesis of new tricyclic ring systems containing the pyrimido[5, 4‐ b ][1, 4]oxazine skeleton
Author(s) -
Mátyus Péter,
Szalay Luca,
Kasztreiner Endre,
Jerkovich Gyula,
Rabloczky György
Publication year - 1989
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570260341
Subject(s) - chemistry , tricyclic , ring (chemistry) , oxazines , stereochemistry , skeleton (computer programming) , organic chemistry , computer science , programming language
Synthesis of derivatives 4 and 6 of two novel tricyclic ring systems, 1, 2, 4‐triazolo[3, 4‐ c ]pyrimido[5, 4‐ b ]‐[1, 4]oxazine and imidazo[1, 2‐ c ]pyrimido[5, 4‐ b ][1, 4]oxazine, respectively is described. Although the parent pyrimido[5, 4‐ b ]oxazines possess positive inotropic activity, the tricyclic compounds are practically inactive.