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Synthesis of 3‐carboethoxy‐4,11‐dihydro‐11‐alkyl/phenyl‐4‐oxopyrimido[1,2‐ b ][1,2,4]benzothiadiazine 6,6‐dioxides. A novel heterocyclic ring system
Author(s) -
Murthy M. S. R.,
Nageswar Y. V. D.,
Reddy A. V. Narender,
Ramalingam T.,
Sattur P. B.
Publication year - 1989
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570260241
Subject(s) - benzothiadiazine , chemistry , alkyl , ring (chemistry) , stereochemistry , medicinal chemistry , organic chemistry
The synthesis of some novel 3‐carboethoxy‐4,11‐dihydro‐11‐alkyl/phenyl‐4‐oxopyrimido[1,2‐ b ][1,2,4]benzo‐thiadiazine 6,6‐dioxides ( IVa‐c ) from 3‐amino‐4‐alkyl/phenyl‐4 H ‐1,2,4‐benzothiadiazine 1,1‐dioxides ( 1a‐c ) and diethyl ethoxymethylenemalonate ( II ) is described. The compounds have been screened for their antibacterial activity.