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Synthesis of 1‐hydroxy‐2 H ,5 H ‐dihydroisoxazolo[5,4‐ c ]quinoline. A novel heterocyclic ring system
Author(s) -
Ruhland Béatrice,
Leclerc Gérard
Publication year - 1989
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570260240
Subject(s) - quinoline , chemistry , tautomer , ring (chemistry) , carbamate , stereochemistry , medicinal chemistry , combinatorial chemistry , organic chemistry
The synthesis of a new heterocyclic compound, 3a , combining a quinoline and a isoxazolol ring is described. The preparation involves cyclisation of the carbamate 14 , followed by concomitant deprotection of the acidic and amino functions to give compound 3a , the stable tautomeric form of 3 .
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